TABLE 3.
Current reports related to circRNAs in modulating miRNA-regulated ferroptosis progression.
| circRNA | Target | Biofunction | Cancer types | Ferroptosis progression | Cell lines | References |
| circ-0008035 | miR-599/EIF4A1 | Inhibiting miR-599 | Gastric cancer | Up | GE8-1 HGC-27 AGS | Li et al., 2020 |
| circ-TTBK2 | miR-761/ITGB8 | Inhibiting miR-761 | Glioma | Down | LN229 U251 NHA | Zhang H. Y. et al., 2020 |
| circ-clARS | ALKBH5 (RBP) | Siliencing ALKBH5 | HCC | Up | HepG2 SMMC-7721 Huh-7 | Liu Z. et al., 2020 |
| circ-IL4R | miR-541-3p/GPX4 | Sponging miR-541-3p | HCC | Down | THLE-2 HuH-7 HCCLM3 | Xu et al., 2020 |
| circ-EPSTI1 | miR-375/miR-409-3p/miR-515-5p-SLC7A11 | Sponging miRNAs to upregulate SLC7A11 expression | Cervical cancer | Up | CaSki HeLa HcerEpic | Wu et al., 2021 |
| circ-RHOT1 | miR-106a-5p/STAT3 | Contributing to malignant progression and attenuating ferroptosis | Breast cancer | Down | MDA-MB-231 T47D | Zhang et al., 2021a |
| circ-0007142 | miR-847-3p/GDPD5 | Upregulating GDPD5 and reversing miR-847-3p-mediated tumor inhibition | CRC | Down | HCT116 SW620 SW480 | Wang et al., 2021 |