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Uterine LMS with ALK rearrangement. a The tumor is highly cellular and composed of interlacing long fascicles of spindle cells with diffuse moderate to focally severe cytologic atypia. b Mitotic figures are increased. The tumor cells are positive for desmin (strong and diffuse) (c) and h-caldesmon (strong and diffuse) (d). LMS, leiomyosarcoma; ALK, anaplastic lymphoma kinase.
