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. 2021 Jun 21;11:693063. doi: 10.3389/fonc.2021.693063

Table 2.

Surgical results and postoperative complications in the 102 patients who underwent transsphenoidal endoscopic surgery for pituitary adenomas in Knosp Grade 4.

Variable Value
Extent of resection
GTR (%) 72 (70.6)
STR (%) 18 (17.6)
PTR (%) 12 (11.8)
Extent of CS resection
GTR (%) 82 (80.4)
STR (%) 17 (17.6)
PTR (%) 3 (2.0)
Intraoprative variables
Mean operation time (min) 158.5
Mean intraoperative hemorrhage (ml) 456.7
Firm consistency (%) 31 (30.4)
ICA rupture (%) 2 (2.0)
CSF leakage (%) 11 (10.8)
Postoperative variables
Headache 33
Better (%) 22 (66.7)
No change (%) 11 (33.3)
Visual dysfunction 38
Better (%) 28 (73.7)
No change (%) 10 (26.3)
Hormone remission 40
Yes (%) 29 (72.5)
No (%) 11 (27.5)
Postoperative complications
abducens nerve palsy (%) 3 (2.9)
oculomotor nerve palsy (%) 4 (3.9)
CSF leakage (%) 6 (5.9)
CNS infection (%) 5 (4.9)
Monocular blindness (%) 2 (2.0)
Panhypopituitarism (%) 3 (2.9)
Permanent diabetes insipidus (%) 2 (2.0)
Follow-up treatments
Radiotherapy (%) 12 (11.8)
Medical therapy (%) 5 (4.9)
Recurrence (%) 6 (5.9)

GTR, gross total resection; STR, subtotal tumor resection; PTR, partial tumor resection; CS, cavernous sinus; CSF, cerebrospinal fluid; CNS, Central Nervous System; ICA, Internal carotid artery.