Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 2;12(2):465–487. doi: 10.1016/j.jcmgh.2021.02.010

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

IFNGR1 mRNA is abundant in paraspeckle of T-cell killing resistant HCC cells. (A) RIP analysis of S1 or NEAT1_2 relative expression in S1-tagged HCCML3 or SKhep1 cells with anti-NONO antibody. (B) Venn diagram of mRNAs potentially interacted with NEAT1_2 in S1-tagged HCCML3 or SKhep1 cells, determined by RIP-seq by precipitation with streptavidin. (C) Genome regions of transcripts potentially interacted with NEAT1_2 in S1-tagged HCCML3 or SKhep1 cells. (D) Binding regions of transcripts potentially interacted with NEAT1_2 in S1-tagged HCCML3 or SKhep1 cells. (E) Kyoto Encyclopedia of Genes and Genomes analysis of the overlapped genes in Figure 2B. (F) Heatmap of the top 10 genes of the overlapped genes. (G) Assay for transposase accessible chromatin with RNA-seq at the IFNGR1 locus. (H) RIP analysis of S1-tagged NEAT1_2 interacted with IFNGR1 mRNA with streptavidin. (I) RIP analysis of NONO interacted with IFNGR1 mRNA or S1-tagged NEAT1_2 with anti-NONO antibody. Data are represented as means ± SD (n = 3; ∗P < .05, ∗∗P < .01).