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Overview of comparison between microarray and RNA-seq approaches
| Items | Microarray [99] | RNA-seq [56] |
|---|---|---|
| Principle | Hybridization | High-throughput sequencing |
| Resolution | Several to 100 bps | Single base |
| Reference genome required | Only knowledge about the microarray | The species or closely related species |
| Different isoform | Limited | Yes |
| Discover new transcript | Limited | Yes |
| Non-coding RNA | Limited | Yes |
