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. 2021 Jun 21;15:640835. doi: 10.3389/fnins.2021.640835

TABLE 5.

Abnormal results of cardioreflex tests in different subgroups of COVID-19 patients with associated co-morbidities.

N (%)
CADG (n = 41) p-value CADG-DM (n = 7) p-value CADG-HTA (n = 18) p-value CADG-Syn (n = 16) p-value
CART
Sympathetic function tests
Blood pressure response to standing (OH) 19 (46.30) 0.001 4 (57.10) 0.001 10 (52.90) 0.001 5 (31.20) 0.001
Hand grip test (HG) 39 (94.40) 0.001 7 (100.00) 0.001 18 (100.00) 0.001 15 (93.70) 0.001
Parasympathetic function tests
Heart rate response to Valsalva maneuver 12 (28.90) 0.001 3 (40.00) 0.001 5 (27.70) 0.001 6 (38.50) 0.001
Heart rate response to deep breathing 17 (41.70) 0.001 3 (40.00) 0.001 8 (46.70) 0.001 4 (25.00) 0.001
ANS impairment
Parasympathetic dysfunction 10 (24.00) 0.057 3 (40.00) 0.097 4 (22.20) 0.131 1 (6.20) 0.282
Combined dysfunction 30 (73.20) 0.001 7 (100.00) 0.001 15 (82.40) 0.001 10 (60.00) 0.001
Autonomic neuropathy 32 (78.00) 0.018 6 (83.30) 0.315 15 (82.40) 0.069 11 (66.70) 0.552

CART, cardioreflex test; CADG, COVID-19 group with associated diseases; CADG-DM, COVID-19 group with diabetes mellitus; CADG-HTA, COVID-19 group with hypertension; CADG-Syn, COVID-19 group with syncope.

Results are presented as counts (percent).

Bivariate analysis of severe and mild group with respect to controls is done by chi-squared test.