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. 2021 Jul 5;38(9):807–815. doi: 10.1007/s40266-021-00880-4

Table 2.

Characteristics of TB treatment and outcomes of the cross-sectional population by different age groups (N = 246)

TB characteristics 18–44 y (n = 46) 45–64 y (n = 48) 65–74 y (n = 35) 75–83 y (n = 60) ≥ 84 y (n = 57)
Multi-site TB (%) 10 (21.7) 6 (12.5) 9 (25.7) 17 (28.3) 10 (17.5)
Smear positive (%) 17 (37.0) 25 (52.1) 21 (60.0) 35 (58.3) 31 (54.4)
Culture-positive TB (%)a,b 39 (84.8) 36 (75.0) 30 (85.6) 56 (93.3) 53 (93.0)
Cavitation on chest radiograph (%) 16 (34.8) 15 (31.3) 14 (40.0) 17 (28.3) 15 (26.3)
Use of PZAa,b,c 42 (91.3) 44 (91.7) 30 (85.7) 43 (71.7) 19 (33.3)
Completed therapy (%)a,b,c 45 (97.8) 45 (93.8) 28 (80.0) 47 (78.3) 25 (43.9)
Median duration of initial hospitalization (days)b,c 36.5 38 44 53 61
Died during therapy (%)a,b,c 1 (2.2) 1 (2.1) 6 (17.1) 13 (21.7) 32 (56.1)
Death related to TB (%)a,b,c 1 (2.2) 1 (2.1) 5 (14.3) 12 (20.0) 26 (45.6)
Median time to death (days) 82 10 39 40 48
Time to treatment completion
 Average daysa,b,c 229 252 264 258 302
 < 26 weeks (%) 0 (0) 3 (6.7) 0 (0) 1 (2.1) 0 (0)
 26 to < 39 weeks (%) 32 (71.1) 24 (53.3) 14 (50.0) 26 (55.3) 10 (40.0)
 39 to < 52 weeks (%) 11 (24.4) 15 (33.3) 12 (42.9) 17 (36.2) 8 (32.0)
 ≥ 52 weeks (%)c 2 (4.4) 3 (6.7) 2 (7.1) 3 (6.4) 7 (28.0)
Sputum culture conversion
 Average days 45.4 39.3 38.6 43.2 41.1
 > 2 months (%) 7 (18.4) 9 (25.0) 4 (14.3) 9 (18.0) 7 (17.5)

PZA pyrazinamide, TB tuberculosis

ap-Value < 0.05 comparing those aged < 65 to those ≥ 65 years

bp-Value < 0.05 comparing those aged < 75 to those ≥ 75 years

cp-Value < 0.05 comparing those aged < 84 to those ≥ 84 years