FIGURE 5.

Early Sox9 regulates ribosomal protein expression. (A) Schematic representation of significantly differentially expressed ribosomal proteins from transcriptome and proteome datasets based on Wikipathways (Slenter et al., 2018): WP163 using PathVisio 3 (Kutmon et al., 2015). (B) Rpl38, Rps30/Fau, Nop10, and SBDS expression at 2 h in ATDC5 differentiation in Control and Sox9 RNAi conditions as measured by RT-qPCR. Results were normalized to β-Actin RNA expression and presented relative to t = 0. (C) In similar samples from B; 18S rRNA, 28S rRNA, and 5.8S rRNA expression. Bars represent mean ± SEM. ns = not significant, *p < 0.05, **p < 0.01, ***p < 0.0001.