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. 2021 May 28;22(7):e52154. doi: 10.15252/embr.202052154

Figure 6. Reduced number of GABAAR SSDs after 4‐AP treatment.

Figure 6

  1. The number of receptor SSDs, segmented from the combined receptor clusters of GABAARs and GlyRs, was decreased after 4‐AP treatment (MW test, P < 0.0001).
  2. This was mostly due to the loss of GABAAR SSDs that were segmented from the rendered images of GABAAR detections only (MW, ****P < 0.0001).
  3. The number of GlyR SSDs (based on GlyR detections) was only marginally reduced (MW, **P < 0.01).

Data information: Number of synapses: n = 452 in TTX, n = 583 in 4‐AP condition, from three independent experiments. Mean ± SEM. These analyses are based on the same dataset as in Fig 5.

Source data are available online for this figure.