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. 2021 May 4;25(13):5988–6005. doi: 10.1111/jcmm.16427

FIGURE 7.

FIGURE 7

Effect of lnc23 on PFN1, and PFN1 on myogenic differentiation. (A) Down‐regulated lnc23 significantly elevated the mRNA expression level of PFN1 in DM2, (B) but did not affect the protein expression level of PFN1. (C) Up‐regulated lnc23 significantly decreased the mRNA expression level of PFN1 in GM (D); it also had no dramatic effect on the PFN1 protein. (E) Knockdown experiment resulted in a 60% decrease in PFN1 mRNA expression level (F) and produced a significant increase in mRNA expression level of cell differentiation‐related markers MyoG and MyHC in DM2