Table 3.
Proportion (%) new-borns with TSH = 1 mIU/L in heel prick blood by laboratory and calendar year and by age at heel prick screening and calendar year (both Cochran-Mantel-Haenzel test)
| 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | p-value | |
|---|---|---|---|---|---|---|---|---|---|---|
| Laboratory | ||||||||||
| Zwolle | 78.74 | 85.66 | 84.54 | 74.08 | 76.38 | 75.45 | 77.37 | 75.17 | 75.47 | < 0.0001 |
| Tilburg | 83.84 | 81.77 | 74.96 | 78.16 | 78.52 | 69.46 | 55.27 | 39.9 | 44.21 | < 0.0001 |
| Capelle | 76.16 | 78.85 | 77.18 | 73.29 | 72.56 | 69.99 | 57.71 | 40.6 | 48.98 | < 0.0001 |
| Bilthoven | 80.02 | 84.64 | 80.02 | 73.87 | 78.36 | 69.11 | 52.84 | 43.25 | 50.72 | < 0.0001 |
| Amsterdam | 43.2 | 39.04 | 55.11 | 48.78 | 65.2 | 75.85 | 72.76 | 62.55 | 36.25 | < 0.0001 |
| Age | ||||||||||
| day 3 | 71.27 | 74.62 | 74.77 | 66.58 | 69.64 | 67.69 | 59.02 | 47.00 | 49.81 | < 0.0001 |
| day 4 | 72.71 | 75.73 | 74.76 | 69.55 | 73.08 | 69.79 | 60.21 | 48.97 | 50.30 | < 0.0001 |
| day 5 | 74.19 | 76.27 | 76.37 | 71.59 | 76.04 | 73.57 | 64.05 | 51.89 | 51.92 | < 0.0001 |
| day 6 | 72.08 | 72.00 | 70.72 | 66.78 | 75.46 | 75.66 | 67.33 | 55.27 | 50.41 | < 0.0001 |
| day 7 | 61.44 | 52.78 | 65.08 | 59.22 | 79.39 | 73.92 | 65.44 | 51.93 | 44.94 | 0.0004 |