Table 2.

Full set of values/scores of aggregation propensity predictions from all SARS-CoV-2 proteins using 4 different algorithms.

Protein	CamSol Intrinsic solubility	Tango (beta aggregation propensity)	Amylogram	PASTA (Pairing energy, kJ)	Prone to aggregate
BSA	0.479889	6.513342	0.67476910427	−9.230629	Negative control
Beta-Amyloid	1.103345	22.4587	0.964286175387	−20.171292	Positive control
just Aβ fragment	0.655945	3.635395	0.5936772918	−6.888103	Positive control
3′-to-5′ exonuclease	−1.365414	3.540996	0.780836059694905	−10.987355	No
2-O-Ribose Methyltransferase	−0.503960	7.303587	0.917586033222489	−7.926963	No
3C Like Proteinase	−1.094241	5.254686	0.866995916960981	−12.714527	No
endoRNAse	−0.225170	5.126858	0.889817000611829	−11.885505	No
Envelope protein	−2.915438	25.39225	0.914774818	−29.181144	Yes
Helicase	−1.206905	2.752962	0.885824647794826	−8.055405	No
Leader protein	1.394877	0.2026	0.674893206737557	−5.359897	No
Membrane glycoprotein	−2.887348	26.75686	0.862681744	−34.513196	Yes
Nsp2	−0.623592	4.99456	0.810156395859043	−12.65233	No
Nsp3	−3.745792	5.9662	0.888048791900172	−8.066283	No
Nsp4	−4.727092	19.00763	0.855524114	−32.389486	Yes
Nsp6	−6.013864	36.30086	0.887343189	−32.815411	Yes
Nsp7	0.231983	17.76802	0.889817001	−7.767171	Yes
Nsp8	0.816455	2.594571	0.672595099068358	−6.916269	No
Nsp9	1.063820	7.472212	0.691380284008589	−5.15149	No
Nsp10	−0.040202		0.665628490992486	−5.345617	No
Nsp11	0.964712	0.071538	0.52229465066422	−2.681862	No
Nucleocapsid phosphoprotein	2.216086	4.942186	0.850755764881348	−6.850497	No
ORF3a	−3.400784	19.49843	0.888048792	−26.32989	Yes
ORF6	−0.804210	23.35634	0.866119264	−21.15957	Yes
ORF7a	−1.501395	22.73566	0.816087315	−16.067259	Yes
ORF7b	−3.341397		0.858967046	−21.061641	Yes
ORF8	−1.072771	10.9687	0.83488134871516	−10.071886	No
ORF10	−1.501395	18.52229	0.804993185	−10.10498	Yes
RNA-dependent RNA polymerase	−1.702360		0.6386355287	−9.090557	No
Surface Glycoprotein	−3.379700	26.76	0.862681743572924	−16.434159	No