Table 4.
Prediction results for studied parameters in all patients groups
| Parameter | Groups | Area under the curve |
Cut off
value |
Sensitivity % | Specificity % | OR | PPV | NPV |
|---|---|---|---|---|---|---|---|---|
| Overgrowth | 0.783 | 172.938 | 80.0 % | 75.0 % | 12.000 | 72.70% | 81.80% | |
| Total leukocytic count | Neurofibromatosis | 0.692 | 8.200 | 80.0 % | 58.3 % | 5.600 | 61.50% | 77.80% |
| Chromosomal breakage | 0.769 | 10.400 | 36.4 % | 91.7 % | 6.286 | 80.00% | 61.10% | |
| Overgrowth | 0.800 | 10.250 | 40.0 % | 91.7 % | 7.333 | 80.00% | 64.70% | |
| Telomerase activity | Neurofibromatosis | 0.725 | 0.278 | 88.9 % | 75.0 % | 24.000 | 72.70% | 90.00% |
| Chromosomal breakage | 0.904 | 0.862 | 45.5 % | 83.3 % | 4.167 | 71.40% | 62.50% | |
| Overgrowth | 0.602 | 0.028 | 100.0 % | 33.3 % | --- | 52.90% | 100.00% | |
|
Nitric
Oxide |
Neurofibromatosis | 0.598 | 10.170 | 70.0 % | 100.0 % | 5.000 | 100.00% | 80.00% |
| Chromosomal breakage | 0.864 | 9.746 | 72.7 % | 100.0 % | 5.000 | 100.00% | 80.00% | |
| Overgrowth | 0.606 | 9.746 | 60.0 % | 100.0 % | 4.000 | 100.00% | 75.00% | |
| GSH | Neurofibromatosis | 0.818 | 1.478 | 90.0 % | 58.3 % | 12.600 | 64.30% | 87.50% |
| Chromosomal breakage | 0.558 | 1.331 | 72.7 % | 66.7 % | 5.333 | 66.70% | 72.70% | |
| Overgrowth | 0.657 | 1.860 | 50.0 % | 75.0 % | 3.000 | 62.50% | 64.30% | |
| GST | Neurofibromatosis | 0.742 | 501.945 | 80.0 % | 91.7 % | 44.000 | 88.90% | 84.60% |
| Chromosomal breakage | 0.529 | 150.443 | 81.8 % | 75.0 % | 13.500 | 75.00% | 81.80% |
OR: odd ratio; PPV: positive predictive value; NPV: negative predictive value