Fig. 1.

Point-of-Care antigen testing (POCT) versus the conventional approach in COVID-19 suspects prior to hospitalization

Legend to Fig. 1:A decision node (square) indicates a choice facing the decision maker or the consequences of a decision. Branches from a chance node (circles) represent the possible outcomes of an event; terminal nodes (triangles) denote the endpoints of a scenario and are assigned the costs of a prior series of actions and events. The arrows in the decision notes pointing downwards demonstrate that the optimal path of the model is that with the lowest total cost. ER: Emergency room; POCT: Point-of-Care antigen testing; RT-PCR: Reverse Transcriptase-PCR; COVID_prev: Prevalence of COVID-19 [reference 3 (Supplement)], Sofia_COVID_sens: Real life sensitivity of Sofia test [reference 12 (Supplement)]: Sofia_Covid_spec: Real life specificity of Sofia testing [reference 12 (Supplement)]; Clin_sens_COVID: Sensitivity of diagnosing SARS-CoV-2 infection [reference 8 (Supplement)]; Clin_spec_COVID: Probability of correctly excluding SARS-CoV-2 [reference 8 (Supplement)].

#: Complementary probability (all probabilities of chance node's branches to sum to 1.0); +: positive; -: negative.