Table 1.

Input for cost–benefit analysis.

Variables Category	Variable Name	Distribution *	Value (Base Case)	Relative Change (Range)	Reference
Prevalence of COVID-19	COVID_prev	PERT	0.156	0.079–0.412	[3 (Supplement)]
Additional revenue per day due earlier discharge	cRev_day_POCT	uniform	€323.91	±20% (€259.13–€388.69)	Calculated using data from the Institut für das Entgeltsystem im Krankenhaus (InEK) [20 (Supplement)]
Real life specificity of Sofia testing	Sofia_COVID_spec	uniform	0.989	95% CI (0.958–0.998)	[12 (Supplement)]
Opportunity costs due to blocking twin bed	cOpp_POCT	uniform	€690.92	±20% (€522.74–€829.1)	Calculated from InEK data [20 (Supplement)]
Probability of correctly excluding SARS-CoV-2	Clin_spec_COVID	PERT	0.683	95% CI (0.60–0.758)	[8 (Supplement)]
Sensitivity of diagnosing SARS-CoV-2 infection	Clin_sens_COVID	PERT	0.806	95% CI (0.729–869)	[8 (Supplement)]
Costs of enoxaparin per day	cAntithromb_day	uniform	€7.09	±20% (€5.67–€8.51)	Rote Liste [Red List] 2021
Costs of Sofia SARS-CoV FIA®	cSofia_COVID	uniform	€12	±20% (€9.6–€14.40)	As declared by manufacturer
Real life sensitivity of Sofia test	Sofia_COVID_sens	PERT	0.80	95% CI (0.644–0.909)	[12 (Supplement)]
Secondary cases due to one unknown COVI-19 case	sec_COVID	PERT	0.025	95% CI (0.013–0.05)	[17 (Supplement)]
Costs of productivity loss per day	cPL_day	uniform	€167.58	±20% (€134.06–€201.1)	Calculated from [27 (Supplement)]
Number of days of health care workers out of work due to COVID-19	sick_days	uniform	15	+12 (27)	[25 (Supplement)]
Probability that hospitalization is required	pHosp	PERT	0.1010	95% CI (0.097–0.1050)	[14 (Supplement)]
Costs of RT-PCR performed in external laboratory	cRT-PCR_ext	uniform	€42.74	+20% (€51.29)	Nationwide laboratory inquiry

^⁎in probabilistic sensitivity analysis.