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. 2021 Mar 17;23(7):1349–1355. doi: 10.1038/s41436-021-01135-8

Table 1.

Indication for testing, overall and by testing year.

Indication Year 1 Year 2 Year 3 Overall Positivity rate
Maternal age 52.9% 54.1% 52.5% 52.9% 3.9%
Ultrasound findings 22.0% 16.7% 12.0% 16.7% 12.5%
No known high-risk indication 3.0% 7.2% 16.6% 9.0% 2.3%
Multiple indications 7.9% 8.1% 6.3% 7.8% 9.1%
Personal/family history 5.8% 5.2% 3.9% 4.9% 3.1%
Serum biochemical screening 5.7% 4.6% 4.0% 4.7% 4.6%
Other high-risk indication 2.9% 4.1% 4.8% 4.0% 2.2%

The right-most column shows the positivity rate for each indication.