Table 3.
Multivariate analysis.
Outcomes | N | HR (95% CI) | P value |
---|---|---|---|
Overall survival | |||
Main effect | |||
Chemotherapy | 261 | Reference | |
Allogeneic HCT | 217 | 2.00 (1.50–2.66) | <0.001 |
Body mass index (kg/m2) | |||
<30 | 332 | Reference | |
≥30 | 146 | 2.17 (1.63–2.89) | <0.001 |
Disease-free survival | |||
Main effect | |||
Chemotherapy | 261 | Reference | |
Allogeneic HCT | 215 | 1.62 (1.25–2.12) | <0.001 |
Body mass index (kg/m2) | |||
<30 | 331 | Reference | |
≥30 | 145 | 1.97 (1.51–2.57) | <0.001 |
Relapse | |||
Allogeneic HCT vs. chemotherapy ≤ 15 months after CR1 | 1.78 (1.10–2.88) | 0.02 | |
Allogeneic HCT vs. chemotherapy > 15 months after CR1 | 0.34 (0.19–0.62) | <0.001 | |
Body mass index (kg/m2) | |||
<30 | 331 | Reference | |
≥30 | 145 | 1.84 (1.31–2.59) | <0.001 |
Non-relapse mortality | |||
Main effect | |||
Chemotherapy | 261 | Reference | |
Allogeneic HCT | 215 | 5.41 (3.23–9.06) | <0.001 |
Body mass index (kg/m2) | |||
<30 | 331 | Reference | |
≥30 | 145 | 2.10 (1.37–3.23) | <0.001 |