Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 1;35(7):1933–1948. doi: 10.1038/s41375-020-01095-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a The endogenous expression of miR-10a in the NCI-60 cell line panel was correlated to sensitivity to 265 drugs screened in GDSC and Nutlin-3a was found to have the 4th strongest positive correlation with an r² value of 0.17 (p < 0.05). b NCI-60 cell lines with endogenous expression below the median level had a mean IC₅₀ of 34.1 µM, versus 95.7 µM for those above. c miR-10a displayed bimodal expression in 86 NPM1^wt primary AML specimens assayed at diagnosis. (*p < 0.05, **p < 0.01; ***p < 0.001 by Student’s T test with error bars representing SD).