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. 2021 May 10;5(7):927–938. doi: 10.1038/s41559-021-01448-6

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© The Author(s), under exclusive licence to Springer Nature Limited 2021, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a, Distribution of core transcription factors crucial for regulating lens development and key optic gene families in multiple metazoans; the ‘+’ and ‘−’ symbols indicate eyes with and without lenses, respectively. b, Phylogenetic analysis of NRL/MAF superfamily from representative metazoans. The phylogenetic tree was constructed using MrBayes under a mixed model of amino acid substitution. The degree of support for internal branching is shown as a probability percentage at the base of each node. Notably, the large MAF only preserves one copy in molluscs but diverges into four clades in vertebrates. N. pompilius is the only extant species that has lost NRL. c, Phylogenetic analysis of crystallin superfamily from representative metazoans. Coleoid cephalopods, N. pompilius and non-cephalopod metazoans are indicated by the black, red and grey branches, respectively. For detailed results, see Supplementary Fig. 10.