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. 2021 Jun 21;9:685741. doi: 10.3389/fcell.2021.685741

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Copyright © 2021 Xiao, Yin, Wang, Yang, Ma, Pan and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential expression and hierarchical cluster analysis of miRNAs, and mRNAs. Volcano plots of significantly differentially expressed RNAs. The red and green dots indicate upregulated and downregulated genes, respectively. The horizontal dotted lines represent a p-value of 0.05, and the vertical dotted lines represent a fold change of 1.5-fold. Heat maps of the RNA expression hierarchical patterns. (A,B) Volcano plots of differentially expressed miRNAs, mRNAs. (C,D) Heat maps of differentially expressed miRNAs, mRNAs.