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. 2021 Jun 1;78(13):5341–5370. doi: 10.1007/s00018-021-03846-2

Fig. 5.

Fig. 5

Relationships between microscopic and macroscopic kinetics of channel opening. Deactivation is a macroscopic property resulting from the integration of single-channel currents time-courses. Its characteristic time (τ) is longer than mean channel open time due to possible channel reopening events and is increased by desensitization due to the possible reactivation of desensitized channels