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. 2021 Jun 1;78(13):5341–5370. doi: 10.1007/s00018-021-03846-2

Table 1.

Examples of Markovian steady-state models used for GABAA receptor study

Model States Conditions of application
MWC Close, open (both bound to 0, 1 or 2 GABA) Macroscopic scale
Flip model Resting, resting bound to GABA, pre-sensitized bound, open bound Macroscopic scale
Resting-activated-desensitized Resting, open, desensitized (all bound to 0, 1 or 2 GABA) Desensitizing receptors
Chang and Weiss model Close (bound to 0–3 GABA), open ρ-Containing receptors