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Properties conferred by the “third subunit class” of the receptor
| Isoform | γ1 | γ2L | γ3 | δ | ε | π |
|---|---|---|---|---|---|---|
| Conductance | Medium | Medium | Medium | Low | Low | Medium |
| GABA EC50 | Medium | Medium (γ2L variant) or moderate (γ2S variant) | Moderate | Low | Medium | Moderate |
| Hill coefficient | Medium | Medium | Medium | Medium | Low | Medium |
| Desensitization | Complete and moderately fast | Slow and incomplete | Fast | |||
| Deactivation | Medium | Moderately fast | ||||
| Activation | Fast | Slow |
