Fig. 4.

Alternative splicing in the C-terminal region of GluN1. A We detected all four C-terminal isoforms, which originate from incorporation of an alternative exon (ae) and the presence of two different acceptor sites in exon 19 [124]. B A comparison of splicing in different datasets (n = 33) shows a positive correlation between incorporation of the alternative exon (A⁺) and usage of the alternative acceptor site (B⁺). For other species, see Fig. S19. C A correlation analysis indicates that the absence or presence of the alternative exon (A⁻/A⁺) predicts the choice of the acceptor site (B⁻/B⁺; left), but not vice versa (right). D Resulting probability diagram for splicing to the alternative acceptor site