Table 3.
Comparison of KRAS mutational status in FFPE tumoral tissues and cfDNA.
| Tumour tissue | Plasma | ||
|---|---|---|---|
| pt id | FFPE TISSUE KRAS mutations |
cfDNA KRAS mutations |
cfDNA KRAS allele frequency |
| COL 01 | KRAS p.G12D | KRAS p.G12D | 0.83 |
| COL 02 | KRAS p.G12C | KRAS p.G12C | 65.26 |
| COL 03 | KRAS p.G12A | KRAS p.G12A | 7.25 |
| COL 04 | KRAS p.G12D | KRAS p.G12D | 30.33 |
| COL 05 | KRAS p.G13D | KRAS p.G13D | 13.68 |
| COL 06 | KRAS p.G12C | KRAS p.G12C | 1.92 |
| COL 07 | KRAS p.G12S | KRAS p.G12S | 38.19 |
| COL 08 | KRAS p.G12D | KRAS p.G12D | 1.36 |
| COL 09 | KRAS p.G13D | KRAS p.G13D | 28.78 |
| COL 10 | KRAS p.G13D | KRAS p.G13D | 2.40 |
| COL 11 | KRAS p.G12D | KRAS p.G12D | 2.78 |
| COL 12 | KRAS p.G12A | KRAS p.G12A | 38.00 |
| COL 13 | KRAS p.G13D | KRAS p.G13D | 0.38 |
| KRAS p.G12D | 1.88 | ||
| COL 14 | KRAS p.G12A | KRAS p.G12D | 1.83 |
| COL 15 | KRAS p.G13V | WT | |
| COL 16 | KRAS p.G12D | KRAS p.G12D | 0.56 |
| COL 17 | KRAS p.A146K | WT | |
| COL 18 | KRAS p.G12D | KRAS p.G12D | 21.81 |
| COL 19 | KRAS p.G12C | KRAS p.G12C | 10.75 |
| COL 20 | KRAS p.G12D | nd | nd |
FFPE formalin fixed paraffin emebedded, nd not determined.