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. 2021 Jul 5;8:25. doi: 10.1038/s41439-021-00156-8

Fig. 1. Structural model of the homeodomain in human PAX4.

Fig. 1

a The human PAX4 homeodomain is represented as cylinders, with the Arg192 and Glu203 residues being shown as sticks. The PAX4 homeodomain consists of three helices: helix-1 (light-blue), helix-2 (green), and helix-3 (yellow). Arg192 located on helix-2 is predicted to form salt-bridges with Glu203 located on helix-3. b Binding of the human PAX4 homeodomain to double-stranded DNA. DNA is shown by ribbon representation in blue. Arg192 of PAX4 (sticks) is predicted to bind with the phosphate backbone (sticks) of DNA.