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. 2021 Jul 5;7:86. doi: 10.1038/s41523-021-00292-y

Fig. 4. Association between germinal center formation in lymph nodes and prognosis in HR-negative breast cancers.

Fig. 4

Kaplan–Meier curves: a invasive Disease-Free Survival (iDFS), b distant Disease-Free Survival (dDFS), c Overall Survival (OS), d invasive Disease-Free Survival (iDFS) in TNBC, e distant Disease-Free Survival (dDFS) in TNBC, and f Overall Survival (OS) in TNBC, according to stromal tumor-infiltrating lymphocytes (TILs) and germinal center (GC) number. Patient groups were stratified by TILs (≥20%, <20%) and the number of GCs (≤ 2GCs, > 2GC) in all assessed cancer-free LNs, as categorical variables. P values correspond to likelihood ratio tests.