Table 2.
Characteristics of the study population: women of childbearing age (Validation set—Group 2).
| Group 2 (n = 126)† | ||||
|---|---|---|---|---|
| A-AD | NA | NA-AD | NA-NAD | |
| Subjects n | 14 | 111 | 47 | 64 |
| Age (years) mean (range) | 33.0 (25–39) | 33.3 (18–42) | 33.0 (18–42) | 33.5 (22–41) |
| BMI (kg/m2) before pregnant mean (range) | 23.50 (18.46–34.37) | 23.28 (15.94–39.91) | 23.35 (17.63–37.29) | 23.23 (15.94–39.91) |
| Social class | ||||
| Managers-technicians/skilled/semiskilled-unskilled/unemployed % | 28.6/50.0/14.3/7.1 | 39.6/20.7/18.0/21.6 | 29.8/19.1/23.4/27.7 | 46.9/21.9/14.1/17.2 |
| Educational level | ||||
| Incomplete secondary or less/complete secondary/university % | 7.1/35.7/57.1 | 11.7/28.8/59.5 | 14.9/31.9/53.2 | 9.4/26.6/64.1 |
| Smoking during pregnancy, Yes/No n/n | 2/12 | 14/97 | 4/43 | 10/54 |
| Smoker, Yes/No n/n | 3/11 | 13/98 | 6/41 | 7/57 |
| Other atopic disorders, yes | 14 (100%)b | 47 (42%)a | 47 (100%) | – |
| Allergic rhinitis, yes | 14 (100%)b,c | 34 (31%)a | 34 (72%)a | – |
| Atopic dermatitis, yes | 5 (36%)b | 13 (12%)a | 13 (28%) | – |
| Allergic conjunctivitis, yes | 8 (57%)b | 20 (18%)a | 20 (43%) | – |
| Food allergy, yes | 1 (7%) | 7 (6%) | 7 (15%) | – |
| Drug allergy, yes | 3 (21%) | 8 (7%) | 8 (17%) | – |
| Parental asthma, yes | 3 (21%) | 12 (11%) | 5 (11%) | 7 (11%) |
| Parental allergic rhinitis, yes | 7 (50%) | 34 (31%) | 19 (40%) | 15 (23%) |
| Parental atopic dermatitis, yes | 2 (14%) | 11 (10%) | 6 (13%) | 5 (8%) |
| Antibiotics consumption, yes | 1 (7%) | 32 (29%) | 12 (26%) | 20 (31%) |
| Paracetamol consumption, yes | 8 (57%) | 67 (60%) | 31 (66%) | 36 (56%) |
| Inhaled corticosteroids consumption, yes | 2 (14%)b,d | 1 (1%)a | 1 (2%) | 0 (0%)a |
| Injectable corticosteroids consumption, yes | 0 (0%) | 2 (2%) | 1 (2%) | 1 (2%) |
| Blood leucocyte count /µl, mean (range) | 8537 (7050–11,570) | 9268 (5180–15,310) | 9258 (5760–14,090) | 9276 (5180–15,310) |
| Blood monocyte count /µl, mean (range) | 630 (450–960) | 595 (320–1280) | 601 (360–1030) | 590 (320–1280) |
| Blood lymphocyte count /µl, mean (range) | 2035 (1270–2650) | 2002 (990–3790) | 1988 (1110–3790) | 2013 (990–3700) |
| Blood basophil count /µl, mean (range) | 34 (20–60) | 34 (0–90) | 37 (10–80) | 33 (0–90) |
| Blood eosinophil count /µl, mean (range) | 234 (90–510)b,c,d | 146 (20–430)a | 159 (20–430)a | 135 (30–430) a |
| Blood neutrophil count /µl, mean (range) | 5604 (4390–8320) | 6491 (3470–10,990) | 6473 (3510–9790) | 6504 (3470–10,990) |
| Season at sampling | ||||
| Winter/spring/summer/autumn % | 0.0/35.7/35.7/28.6 | 3.6/32.4/41.4/22.5 | 2.1/36.2/38.3/23.4 | 4.7/29.7/43.8/21.9 |
A-AD asthmatics with other coexisting atopic diseases; NA non-asthmatics; NA-NAD non-asthmatics without atopic diseases; NA-AD non-asthmatics with other atopic diseases.
aSignificantly different (p-value < 0.05) from asthmatics with coexisting other atopic diseases (A-AD).
bSignificantly different (p-value < 0.05) from non-asthmatics (NA).
cSignificantly different (p-value < 0.05) from non-asthmatics with other atopic diseases (NA-AD).
dSignificantly different (p-value < 0.05) from non-asthmatic without atopic diseases (NA-NAD).
†One woman was not included in any of the four categories for being asthmatic without other atopic diseases.