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. 2021 Jul 5;7:35. doi: 10.1038/s41537-021-00164-1

Fig. 1. Comparison of microRNA expression levels between patients with early-onset and adult-onset schizophrenia, unaffected relatives of patients with schizophrenia, patients with bipolar disorder, and healthy controls.

Fig. 1

a The expression levels of the four-miRNA in the peripheral blood of EOS, AOS and HC. b The expression levels of the four-miRNA in the peripheral blood of REOS, RAOS and HC. c The expression levels of the four-miRNA in the peripheral blood of EOS, AOS and BD. d The expression levels of the four-miRNA in the peripheral blood of REOS, RAOS and BD. e Receiver operating characteristic (ROC) curve analysis of miR-137 expression levels between patients with early-onset schizophrenia and healthy controls. f ROC curve analysis of miR-34b expression levels between early-onset and adult-onset schizophrenia. AOS adult-onset schizophrenia, EOS early-onset schizophrenia, RAOS unaffected first-degree relatives of AOS patients, REOS unaffected first-degree relatives of EOS patients, BD bipolar disorder, HC healthy controls. *p < 0.05; **p < 0.01; ***p < 0.001. Error bars represent standard errors of the mean.