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. 2021 Jun 14;28(7):2145–2159. doi: 10.1038/s41418-021-00743-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — The qPCR analysis of circRNA-ARC1 (ARC1) in response to the knock down of AR in C4-2 and CWR22Rv1 cells (A), and in T24 and TCC-SUP cells (B). Effect of Enz treatment on expression of circRNA-ARC1 in PCa and BCa cell lines. The qPCR analysis of ARC1 expression after Enz treatment in CWR22Rv1 cell line (C) and in UMUC3 and T24 cells (D). RNase R-digestion assay to confirm circularity of ARC1 in C4-2 cells (E) and T24 cells (F). Data are presented as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001.