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. 2021 Jul 5;12:4126. doi: 10.1038/s41467-021-24341-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Western blot showing knockdown of DHX9 by two different siRNAs, DHX9(7) and DHX9(utr) in U2OS cells. GAPDH is indicated as a loading control. b Clonogenic survival assay showing that cells knocked down for DHX9 are hypersensitive to DNA damage caused by treating cells with camptothecin and c Olaparib. d Graph of percentage cell viability after treatment of indicated cells with ionizing radiation measured by counting live cells in a Casey Cell counter. Cells depleted of DHX9 exhibit no decrease in viability compared to wild-type cells. Graphs include data from three biologically independent experiments. Statistical significance was determined using one-way ANOVA with Tukey’s post hoc test (****p < 0.0001, ****p < 0.0001, ***p < 0.001, *p < 0.1, ns not significant). Mean and error bars indicating one standard deviation are also indicated. Source data are provided as a Source Data file.