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. 2021 Jul 5;8:49. doi: 10.1186/s40658-021-00396-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — Example of segmentation for a massive PE (red) using the MaxTh method (first row), the Zth method (second row), and the RelDiffTh method (third row). Ground truth is delineated in blue. MaxTh showed good correlation in PVOI assessment, but wrongly delineated areas without PE. RelDiff Method showed an underestimation of PVOI, but a good spatial agreement