Table 2.
Anthropometric, body composition and laboratory parameters of T2DM patients with and without sarcopenia.
| Parameters | Non-sarcopenic (n = 67, 74.4%) | Sarcopenic (n = 23, 25.6%) | P |
| BMI (kg/m2)∗ | 32.46 ± 5.80 | 36.85 ± 5.93 | .003 |
| WC (cm)∗ | 110.69 ± 11.96 | 117.49 ± 12.37 | .025 |
| HC (cm)∗ | 113.17 ± 12.70 | 121.05 ± 12.11 | .013 |
| WHR (cm)∗ | 0.97 ± 0.082 | 0.97 ± 0.084 | .623 |
| CC (cm)∗ | 40.92 ± 5.51 | 44.13 ± 5.31 | .017 |
| MAC (cm)∗ | 35.62 ± 4.30 | 37.26 ± 5.15 | .139 |
| FM (kg)∗ | 32.52 ± 12.21 | 42.43 ± 12.76 | .002 |
| FFM (kg)∗ | 51.18 ± 7.96 | 50.80 ± 7.72 | .843 |
| ASM (kg)∗ | 28.97 ± 4.50 | 28.75 ± 4.37 | .842 |
| ASM (%)∗ | 35.14 ± 5.32 | 31.28 ± 4.08 | .002 |
| SMI (kg/m2)∗ | 11.17 ± 1.22 | 11.33 ± 0.96 | .587 |
| FMI (kg/m2)∗ | 12.75 ± 5.06 | 16.83 ± 4.97 | .001 |
| FFMI (kg/m2)∗ | 19.74 ± 2.16 | 20.02 ± 1.70 | .586 |
| GS (s)∗ | 6.62 ± 1.80 | 6.74 ± 1.61 | .776 |
| HGS (kg)∗ | 25.11 ± 8.96 | 19.65 ± 6.39 | .009 |
| Myostatin∗ | 44.95 ± 13.47 | 48.94 ± 8.68 | .108 |
| Irisin∗ | 13.67 ± 9.07 | 10.07 ± 6.17 | .038 |
| FPG (mg/dl)∗ | 164.82 ± 60.23 | 180.69 ± 56.33 | .259 |
| A1c (%)∗ | 7.99 ± 1.81 | 9.09 ± 1.96 | .016 |
| < 7 (n,%)† | 28 (41.8) | 2 (8.7) | .002 |
| ≥7 (n,%)† | 39 (58.2) | 21 (91.3) | |
| Total-C (mg/dl)∗ | 171.56 ± 40.38 | 186.69 ± 45.82 | .169 |
| LDL-C (mg/dl)∗ | 111.89 ± 38.82 | 129.52 ± 36.13 | .054 |
| HDL-C (mg/dl)∗ | 44.79 ± 10.34 | 42.76 ± 10.08 | .398 |
| TG (mg/dl)‡ | 167.82 ± 91.00 | 170.65 ± 82.91 | .937 |
| ALT (U/L)∗ | 23.02 ± 11.17 | 25.78 ± 17.16 | .478 |
| Cr (mg/dl)‡ | 0.74 ± 0.18 | 0.67 ± 0.16 | .279 |
| eGFR (ml/min)‡ | 109.78 ± 37.98 | 205.46 ± 79.10 | .523 |
| Spot urine protein/Cr (g/g)‡ | 94.60 ± 17.10 | 98.14 ± 11.34 | .627 |
Continuous variables were expressed as the mean ± SD; categorical variables were expressed as a number (percentage).
Independent samples t-tests.
Chi-square χ2 test.
Mann–Whitney U test. P < .05 is significant.
BMI = body mass index; WC = waist circumference; HC = hip circumference; WHR = waist–hip ratio; CC = calf circumference; MAC = mid-arm circumference; FM = fat mass; FFM = fat-free mass; ASM = appendicular skeletal muscle mass; SMI = skeletal muscle index; FMI = fat mass index; FFMI = fat-free mass index; GS = gait speed; HGS = hand grip strength; FPG = fasting plasma glucose; A1C = glycosylated hemoglobin; Total-C = total cholesterol; HDL-C = high-density lipoprotein cholesterol; TG = triglyceride; ALT = alanine aminotransferase; Cr = creatinine; eGFR = glomerular filtration ratio.