Table 4.
The relationship between demographic, anthropometric and metabolic parameters with sarcopenia and SO markers in T2DM.
| Variables | FM/FFM∗ | ASM (%)∗ | FMI∗ | FFMI∗ | HGS∗ | GS∗ | Age∗ | BMI∗ | WHR∗ | CC∗ | MAC∗ | FPG∗ | T-C∗ | LDL-C∗ | HDL-C∗ | TG† | Cr† | eGFR† | Myostatin∗ | Irisin∗ | A1c∗ | |
| FM/FFM | r | – | −0.988 | 0.966 | −0.310 | 0.385 | 0.301 | −0.010 | 0.841 | −0.068 | 0.589 | 0.589 | −0.003 | 0.250 | 0.113 | 0.203 | 0.039 | −0.099 | −0.148 | 0.303 | −0.491 | 0.256 |
| P | – | .000 | .000 | .003 | .000 | .004 | .928 | .000 | .523 | .000 | .000 | .980 | .017 | .287 | .055 | .718 | .355 | .165 | .004 | .000 | .015 | |
| ASM(%) | r | −0.988 | – | −0.947 | 0.311 | 0.426 | −0.296 | 0.027 | −0.815 | 0.079 | −0.564 | −0.552 | −0.024 | −0.281 | −0.119 | 0.221 | −0.046 | 0.122 | 0.143 | −0.351 | 0.494 | −0.279 |
| P | .000 | – | .000 | .003 | .000 | .005 | .801 | .000 | .459 | .000 | .000 | .826 | .007 | .265 | .056 | .664 | .252 | .179 | .001 | .000 | .008 | |
| HGS(kg) | r | −0.385 | 0.426 | −0.461 | 0.273 | – | −0.320 | −0.081 | −0.208 | 0.024 | 0.041 | 0.049 | −0.051 | −0.226 | −0.184 | 0.181 | −0.010 | 0.259 | 0.045 | −0.270 | 0.354 | −0.259 |
| P | .000 | .000 | .000 | .009 | – | .002 | .447 | .049 | .825 | .701 | .649 | .631 | .032 | .082 | .087 | .925 | .054 | .676 | .010 | .001 | .014 | |
| GS(m/s) | r | 0.301 | −0.296 | −0.209 | 0.323 | −0.320 | – | 0.290 | 0.163 | 0.128 | 0.111 | 0.133 | 0.004 | 0.094 | 0.137 | 0.102 | 0.006 | 0.206 | −0.378 | 0.070 | −0.275 | 0.240 |
| P | .004 | .005 | .048 | .002 | .002 | – | .006 | .125 | .229 | .299 | .211 | .970 | .379 | .199 | .340 | .954 | .051 | .055 | .513 | .009 | .023 | |
| FMI | r | 0.966 | −0.947 | – | −0.169 | −0.461 | −0.209 | −0.090 | 0.945 | −0.160 | 0.693 | 0.689 | 0.017 | 0.232 | 0.127 | 0.180 | 0.090 | −0.154 | −0.089 | 0.121 | −0.428 | −0.185 |
| P | .000 | .000 | – | .111 | .000 | .048 | .398 | .000 | .132 | .000 | .000 | .874 | .028 | .231 | .090 | .400 | .147 | .407 | .257 | .000 | .081 | |
| FFMI | r | −0.310 | 0.311 | −0.169 | – | 0.273 | 0.323 | −0.138 | 0.128 | −0.023 | 0.112 | 0.081 | −0.083 | −0.036 | 0.180 | 0.188 | 0.173 | 0.224 | 0.012 | −0.326 | 0.176 | 0.265 |
| P | .003 | .003 | .111 | – | .009 | .002 | .196 | .228 | .829 | .292 | .449 | .437 | .734 | .090 | .066 | .103 | .034 | .914 | .002 | .098 | .012 |
Pearson correlation test.
Spearman correlation test. P < .05 is significant.
A1C = glycosylated hemoglobin, ASM = appendicular skeletal muscle mass, BMI = body mass index, CC = calf circumference, Cr = creatine, eGFR = glomerular filtration ratio, FFMI = fat-free mass index, FM/FFM = fat mass/fat-free mass, FMI = fat mass index, FPG = fasting plasma glucose, GS = gait speed, HDL = high-density lipoprotein cholesterol, HGS = hand grip strength, LDL-C = low-density lipoprotein cholesterol, MAC = mid-arm circumference, SMI = skeletal muscle index, SO = sarcopenic obesity, T2DM = type 2 diabetes mellitus, T-C = total cholesterol, TG = triglyceride, WHR = waist–hip ratio.