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Viability in HB cells transfected with NT or NRP2 siRNA. The number of colonies was decreased ~40% after NRP2 knockdown in HUH6 cells (A–C) and 60% in HB-282 cells at 72 h post-transfection (E–G). ATP concentration decreased 30% after NRP2 silencing both in HUH6 (D) and HB-282 cells (H). Bar plots are presented as relative values of mean of three independent experiments ± RSD. **p-value < 0.01, *p-value < 0.05. NT, non-targeting.
