Table 3.

Predictors of 1-year MI or vascular death in 2015–2018 cohort

Predictor variable	MI or vascular death		Recurrent stroke
	Adjusted* HR (95% CI)	P value	Adjusted* HR (95% CI)	P value
Age, years	1.03 (1.02 to 1.04)	<0.001	1.01 (1.00 to 1.01)	<0.001
Male sex	0.89 (0.67 to 1.18)	0.405	1.06 (0.94 to 1.19)	0.381
NIHSS >6	1.91 (1.46 to 2.49)	<0.001	1.21 (1.07 to 1.36)	0.002
Final diagnosis of stroke	2.51 (1.11 to 5.68)	0.028	2.20 (1.65 to 2.93)	<0.001
TOAST Classification
Cardioembolism	0.70 (0.43 to 1.14)	0.151	0.88 (0.68 to 1.13)	0.298
Non-cardioembolism	Ref.	Ref.	Ref.	Ref.
Previous stroke/TIA	1.69 (1.30 to 2.20)	<0.001	1.56 (1.40 to 1.75)	<0.001
Previous MI	1.83 (0.96 to 3.47)	0.066	0.99 (0.69 to 1.42)	0.958
Coronary artery disease	1.50 (1.08 to 2.07)	0.015	1.23 (1.04 to 1.45)	0.016
Hypertension	0.95 (0.71 to 1.25)	0.695	1.01 (0.89 to 1.13)	0.937
Diabetes mellitus	1.15 (0.87 to 1.54)	0.332	1.17 (1.04 to 1.32)	0.008
Atrial fibrillation	1.83 (1.20 to 2.80)	0.005	1.14 (0.90 to 1.45)	0.272
Current smoking	0.96 (0.70 to 1.31)	0.799	1.01 (0.89 to 1.15)	0.863
Treatment
Endovascular therapy	2.45 (1.13 to 5.33)	0.024	2.00 (1.21 to 3.29)	0.007
Early antiplatelet	0.47 (0.32 to 0.67)	<0.001	0.70 (0.58 to 0.85)	<0.001
Lipid lowing at discharge	0.39 (0.27 to 0.56)	<0.001	0.70 (0.58 to 0.84)	<0.001
Antihypertension at discharge	0.99 (0.74 to 1.31)	0.922	1.05 (0.93 to 1.17)	0.441

*Adjusted for sex, age, NIHSS >6, history of Previous stroke/TIA, previous MI, known coronary artery disease, hypertension, diabetes mellitus, atrial fibrillation, peripheral artery disease, current smoker and lipid lowering and antihypertensive treatments.

MI, myocardial infarction; NIHSS, National Institutes of Health Stroke Scale; TIA, transient ischaemic attack; TOAST, Trial of Org 10 712 in acute stroke treatment.