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. 2021 Jun 22;9:684643. doi: 10.3389/fcell.2021.684643

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Copyright © 2021 Wu, Zhang, Wei, Feng, Hu, Deng, Liu, Luan, Ruan, Liu, Liu, Liu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan-Meier survival curves analysis stratified by different clinical parameters. (A) Age ≤ 65 (n = 353); (B) age > 65 (n = 186); (C) male (n = 353); (D) female (n = 186); (E) grade 1–2 (n = 249); (F) grade 3–4 (n = 282); (G) stage I–II (n = 331); (H) stage III–IV (n = 205); (I) T stage 1–2 (n = 349); (J) T stage 3–4 (n = 190); (K) N stage 0 (n = 241); (L) N stage 1-X (n = 298); (M) M stage 0 (n = 428); (N) M stage1-X (n = 109) (the statistical method was a log-rank test for a single factor).