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Screening of and information on compounds 1 and 2: A High-throughput screening for inhibitors targeting PEDV 3CLpro from a library containing 1590 low-MW compounds was conducted. Each dot represents the percentage of inhibition of a compound. Compounds and substrate were used at final concentrations of 1.25 mmol/L and 40 µmol/L, respectively. B The structures and chemical names of compounds 1 and 2.
