Table 3. Comparison of combination therapy versus placebo.

Outcome	Number of studies	Study name (clinical trial or intervention)	Sample size	Estimated effect size
2.1 Time-weighted average change in viral load (in log10 copies per milliliter) during 1st 7days	1	Weinreich 2021 (REGN-COV2)	221	MD = −0.40 [−0.43, −0.37]
2.2 Clinical recovery	1	Gottlieb 2021 (BLAZE-1)	229	RR = 1.24 [0.98, 1.57]
2.3 Hospital visit within 29 days	1	Weinreich 2021 (REGN-COV2)	275	RR = 0.51 [0.17, 1.54]
2.4 Treatment-emergent adverse event	1	Gottlieb 2021 (BLAZE-1)	268	RR = 0.63 [0.39, 1.02]

MD, mean difference; RR, risk ratio.