Table 1.
Symptom | Reference |
---|---|
Self-reported muscle weakness (in 40%–70 %) | [3] |
Reduced grip strength | [31] |
Prolonged chair rising test time | [31] |
Impaired quality of life associated with low muscle strength | [34] |
Low serum creatine kinase | [35] |
Low plasma myoglobin levels | [35] |
Lower IGF1 levels associated with worse myopathy | [63] |
Decreased muscle fiber conduction velocity | [36] |
Decrease of type 1 and type 2A fibers (11% and 17%) | [36] |
IGF1, insulin-like growth factor 1.