Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 22;12:662020. doi: 10.3389/fphar.2021.662020

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Marquez-Exposito, Tejedor-Santamaria, Santos-Sanchez, Valentijn, Cantero-Navarro, Rayego-Mateos, Rodrigues-Diez, Tejera-Muñoz, Marchant, Sanz, Ortiz, Goldschmeding and Ruiz-Ortega.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Loss of protective factors in old kidneys is exacerbated in response to folic-acid (FA) administration. Folic Acid (FA; 125 mg/kg) was injected in 3-months-old (Young) and 1-year-old (Old) C57BL/6 mice and kidneys were studied after 48 h. Kidney Klotho (A) and Ppargc1a (B) gene expression levels were assessed by qRT-PCR. Data are shown as n-fold and expressed as mean ± SD of n = 6-9 animals per group. *p < 0.05 vs. control young mice, ^# p < 0.05 vs. FA-injected young mice, ^& p < 0.05 vs. control old mice. The parametric one-way ANOVA statistical test was performed.