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. 2021 Apr 28;6(7):1949–1960. doi: 10.1016/j.ekir.2021.04.016

Table 2.

Biomarker mean results by BILAG class (N = 341)

A (n = 2) B (n = 25) C (n = 3) D (n = 113) E (n = 39) N/A (n = 159) P value
NGAL, ng/ml, mean (SD)
ELISA
MPL
2.66 (1.98) 4.03 (1.22) 1.87 (2.03) 2.84 (1.37) 3.52 (1.45) 2.80 (1.41) 0.00016
2.15 (0.93) 2.54 (0.47) 1.60 (1.24) 2.20 (0.82) 3.52 (0.57) 2.33 (1.00) 0.232
KIM-1, pg/ml; mean (SD)
ELISA
MPL
5.78 (1.02) 6.82 (0.67) 5.95 (0.63) 5.97 (1.35) 5.99 (1.20) 6.30 (0.99) 0.01
5.78 (0.78) 6.75 (0.71) 6.13 (0.48) 5.87 (1.78) 6.19 (1.10) 6.24 (1.15) 0.0689
MCP-1, pg/ml, mean (SD)
ELISA
MPL
5.53 (0.53) 5.47 (0.75) 4.69 (0.85) 4.60 (1.73) 4.89 (1.20) 5.20 (0.96) 0.00231
5.26 (1.04) 5.48 (0.74) 4.89 (0.81) 4.60 (1.90) 4.75 (1.33) 5.14 (0.93) 0.00978
Adiponectin, ng/ml, mean (SD)
ELISA

MPL
1.71 (0.10) 1.69 (0.18) 1.53 (0.17) 1.55 (0.31) 1.56 (0.26) 1.63 (0.23) 0.0609
1.54 (4.82) 4.11 (0.59) 2.88 (0.61) 2.49 (1.33) 2.78 (0.99) 2.27 (1.44) 7.03 × 10−8
Ceruloplasmin, ng/ml, mean (SD) ELISA 8.80 (4.01) 8.58 (1.05) 7.34 (0.16) 6.77 (1.09) 6.80 (1.02) 7.05 (0.86) 1.44 × 10−13
Hemopexin, ng/ml, mean (SD) ELISA 6.23 (1.87) 7.21 (0.42) 6.51 (0.47) 5.91 (1.06) 5.85 (1.01) 6.29 (0.94) 6.54 × 10−8

BILAG, British Isles Lupus Assessment Group; ELISA, enzyme-linked immunosorbent assay; KIM-1, kidney injury molecule−1; MCP-1, monocyte chemoattractant protein−1; MPL, multiplex platform; NGAL, neutrophil gelatinase−associated lipocalin.