Figure 1.

Neural epidermal growth factor–like 1 (NELL1)–associated membranous glomerulopathy in a patient with graft-versus-host disease. Light microscopy shows segmental glomerular basement membrane thickening with subepithelial spike formation (a, Jones methenamine silver, original magnification ×600). Immunofluorescence staining for immunoglobulin G (IgG) shows granular segmental glomerular capillary wall staining for IgG (b, original magnification ×400) and along tubular basement membranes (c, original magnification ×400). Ultrastructural examination confirms the presence of subepithelial electron dense deposits (d, original magnification ×6000).