Table 1.
Patient no. | Demographics |
HSCT |
Clinical parameters at time of renal biopsy |
Renal biopsy findings |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age, yrs | Sex | Race | Indication for HSCT | GVHD | Interval between HSCT and renal biopsy, mo | sCr, mg/dl |
UPCR, g/g | Serum albumin, g/dl | Edema | Segmental MGN | TBM deposits | PLA2R | NELL1 | Mesangial deposits | |
1a | 74 | M | W | CMML | Y | 36 | 1.46 | 6.8 | 2.5 | Y | Y | Y | neg | pos | N |
2 | 58 | M | Leukemia NOS | Y | 60 | 0.8 | 2.2 | 3.9 | Y | Y | Y | NA | pos | Y | |
3 | 68 | M | MDS | Y | N | N | NA | neg | N | ||||||
4 | 70 | F | W | AML | Y | 54 | 0.8 | 3.3 | 2.6 | Y | N | N | neg | neg | Y |
5 | 53 | M | AML | Y | 48 | 1.3 | Y | N | N | neg | neg | N | |||
6 | 59 | F | W | AML | Y | 48 | 1.4 | 5 | 2.9 | Y | N | N | pos | neg | N |
7 | 55 | M | CML | NA | 60 | 2.3 | 15 | N | N | NA | neg | NA | |||
8 | 73 | F | W | APL | Y | 12 | 0.7 | 5.7 | 2.3 | Y | N | N | neg | neg | N |
9 | 68 | M | W | MCL | Y | 1.2 | 4.5 | 3.7 | N | N | Y | neg | neg | N |
AML, acute myeloid leukemia; APL, acute promyelocytic leukemia; CML, chronic myeloid leukemia; CMML, chronic myelomonocytic leukemia; F, female; GVHD, graft-versus-host disease; HSCT, hematopoietic stem cell transplant; M, male; MCL, mantle cell lymphoma; MDS, myelodysplastic syndrome; MGN, membranous glomerulopathy; N, no; neg, negative; NA, not available/not performed; NELL1, neural epidermal growth factor–like 1; NOS, not otherwise specified; pos, positive; PLA2R, phospholipase A2 receptor; sCr, serum creatinine; TBM, tubular basement membrane; UPCR, urine protein to creatinine ratio; W, white; Y, yes.
Index case that is the subject of this report.