Figure 4.

Closed-loop responses obtained with LIS to an announced meal (left panel), with LIS and different levels of controller’s aggressiveness to an unannounced meal (middle panel), and with $\mathrm{\alpha }$-insulin and different levels of controller’s aggressiveness to an unannounced meal (right panel).

The boundaries of the filled areas represent the 5th and 95th percentiles. LIS, insulin lispro.