Table 2.

Comparison Between Numerical Results Related to Each Set of Closed-Loop Simulations.

	Announced		Unannounced meal						Unannounced meal
	Lispro		Lispro						$\mathrm{\alpha }$-Insulin
Insulin	1		1		2		3		1		2		3
$\mathrm{\alpha }$	Mean	Median [IQR]	Mean	Median [IQR]	Mean	Median [IQR]	Mean	Median [IQR]	Mean	Median [IQR]	Mean	Median [IQR]	Mean	Median [IQR]
Average glucose	130	128 [13]	157	155 [18]	141	140 [12]	138	138 [11]	157	155 [18]	135	135 [8]	131	130 [6]
% time < 50 mg/dL	0	0 [0]	0	0 [0]	0.1	0 [0]	0.2	0 [0]	0	0 [0]	0.1	0 [0]	0.1	0 [0]
% time < 70 mg/dL	0.1	0 [0]	0	0 [0]	0.9	0 [0]	1.4	0 [0]	0	0 [0]	0.6	0 [0]	0.4	0 [0]
% time in [70, 180]	92.9	100 [13]	70.1	67.0 [18]	79.9	77.8 [21]	81.4	79.4 [24]	70.1	67.0 [18]	88.8	88.2 [18]	94.1	100 [11]
% time > 180 mg/dL	7.0	0 [13]	29.9	33.0 [18]	19.2	22.2 [21]	17.2	20.1 [23]	29.9	33.0 [18]	10.6	11.3 [18]	5.5	0 [11]
% time > 250 mg/dL	0	0 [0]	0.6	0 [0]	0.3	0 [0]	0.2	0 [0]	0.6	0 [0]	0	0 [0]	0	0 [0]
LBGI	0.19	0.07 [0]	0.05	0 [0]	0.40	0.11 [0]	0.52	0.18 [1]	0.05	0 [0]	0.21	0.01 [0]	0.14	0 [0]
HBGI	1.83	1.54 [2]	5.29	5.26 [3]	3.56	3.57 [2]	3.28	3.26 [2]	5.29	5.26 [3]	2.4	2.40 [1]	1.66	1.65 [1]

Abbreviations: HBGI, high blood glucose index; IQR, interquartile range; LBGI, low blood glucose index.