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. 2021 May 12;6(7):1840–1849. doi: 10.1016/j.ekir.2021.04.037

Figure 2.

Figure 2

Figure 2

Changes in iron-related parameters (full analysis set). (a) ESA-naïve subjects; (b) ESA-treated subjects. Each point indicates the median value in each treatment arm and bars indicate Q1 and Q3. Post hoc analysis was performed for changes in week 24, which were compared with week 0 using the Wilcoxon signed-rank test and between both arms using the Wilcoxon rank sum test (significance level: 5%, two-sided). Adjustment for multiplicity was not performed. ∗P < 0.05 and ∗∗P < 0.0001 for comparisons with week 0, †P < 0.05 and ††P < 0.0001 for comparisons between both arms. BL, baseline; DA, darbepoetin alfa; ESA, erythropoiesis-stimulating agent; TIBC, total iron-binding capacity; TSAT, transferrin saturation.