TABLE 3:
Comparison of Normalized Signal Intensity (SI) Percentage Changes From Preinjection (Baseline) MR Lymphography (MRL) to Postinjection MRL With Respect to Lymph Node (LN) Disease Status and Time After Ferumoxytol Injection
| 95% Confidence Limits |
|||||
|---|---|---|---|---|---|
| Postinjection Time Point, LNs (Subgroup) or LN Comparison (Subgroups Compared) | Value | SE | Lower | Upper | p |
| Normalized SI percentage change from preinjection MRL to postinjection MRL (%) | |||||
| 24 Hours after ferumoxytol injection | |||||
| Nonmetastatic LNs (A) | −46.9 | 4.0 | −54.8 | −39.0 | |
| Metastatic LNs (B) | −33.6 | 2.9 | −39.2 | −28.0 | |
| 48 Hours after ferumoxytol injection | |||||
| Nonmetastatic LNs (C) | −40.0 | 5.9 | −51.5 | −28.4 | |
| Metastatic LNs (D) | −24.0 | 4.2 | −32.2 | −15.8 | |
| Absolute difference between normalized SI percentage change from preinjection MRL to postinjection MRL (%) | |||||
| 24 Hours after ferumoxytol injection | |||||
| Nonmetastatic vs metastatic LNs (B – A) | 13.3 | 4.4 | 4.6 | 22.0 | 0.003 |
| 48 Hours after ferumoxytol injection | |||||
| Nonmetastatic vs metastatic LNs (D – C) | 16.0 | 6.8 | 2.5 | 29.5 | 0.020 |
| 24 vs 48 hours after ferumoxytol injection | |||||
| Nonmetastatic LNs (C – A) | 6.9 | 6.1 | −5.1 | 19.0 | 0.260 |
| Metastatic LNs (D – B) | 9.6 | 4.2 | 1.4 | 17.9 | 0.023 |
Note—SE = standard error.