Table 3.
Interaction partners of STAC proteins identified by at least two independent proteomics screens or two experimental methods
| Isoform | Binding partner | Functional role | Assay | Reference |
|---|---|---|---|---|
| STAC1 | YWHAE | 14-3-3 protein | AC | (107, 116) |
| ANKLE2 | Mitotic nuclear envelope reassembly, brain development | AC | (116, 117) | |
| KANK2 | Transcriptional regulation | 2H | (118, 119) | |
| NCKIPSD | Stress fiber formation, angiogenesis | 2H | (119, 120) | |
| YWHAZ | 14-3-3 protein | AC | (116, 117) | |
| KIAA1958 | Uncharacterized | 2H | (118, 119) | |
| LZTS2 | Microtubule regulator; Wnt signaling | 2H | (118, 119) | |
| PARP2 | DNA repair | PA, ES | (121) | |
| STAC3 | ZCCHC10 | Uncharacterized | 2H | (118, 119, 122) |
| CSNK2A1 | Serine/threonine-protein kinase complex subunit | 2H | (118, 119, 123) | |
| PPARA | Transcription factor | 2H | (119, 122) | |
| FAM133A | Uncharacterized | 2H | (118, 119) | |
| EAF1 | Transcriptional transactivator | 2H | (119, 124) | |
| ENKD1 | Uncharacterized | 2H | (119, 124) | |
| C1ORF35 | Uncharacterized | 2H | (119, 124) | |
| WDR54 | ERK signaling pathway | AC | (116, 117) | |
| GTF2F1 | Transcription initiation factor | AC | (116, 117) | |
| SREK1IP1 | Splicing regulator | 2H | (118, 119) |
Abbreviations: 2H, two hybrid assay; AC, affinity capture; ES, enzymatic study; PA, protein array; RS, reconstituted complex.
Data curated from the BioGrid, HuRT, IntAct, and UniProt databases.