Table 3.
Elective surgery after acute uncomplicated diverticulitis.
| Study | Year | Design | Main limitations | Main conclusions |
|---|---|---|---|---|
| LASER (71) | 2020 | RCT | Under-powered | Favors surgery |
| DIRECT trial primary outcome: long-term results (70,72) | 2017, 2019 | RCT | Under-powered Limited representativeness |
Favors surgery |
| Polese et al. (68) | 2018 | Retrospective parallel group | Selection bias | Favors surgery |
| Brandlhuber et al. (66) | 2018 | Retrospective parallel group | Selection bias | Favors conservative treatment |
| von Strauss Und Torney et al. (69) | 2017 | Cross-sectional cohort | HRQoL not evaluated, based on administrative data | Decline in proportion of colon resections over time |
| Boostrom et al. (65) | 2012 | Retrospective single cohort | No control group | Improved symptoms after surgery |
| Klarenbeek et al. (67) | 2010 | Retrospective parallel group | Selection bias HRQoL not evaluated |
Favors conservative treatment for majority of patients |
RCT: randomized controlled trial; HRQoL: health-related quality of life.